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Feasibility Study Using GEANT4 Monte Carlo Simulations of a PET Cyclotron-Based Neutron Source for Boron Neutron Capture Therapy
New Phys.: Sae Mulli 2017; 67: 1319~1326
Published online November 30, 2017;
© 2017 New Physics: Sae Mulli.

Jae Won CHOI, Bo Sun KANG*

Department of Medical Science, Konyang University, Daejeon 35365, Korea
Correspondence to:
Received September 18, 2017; Revised October 11, 2017; Accepted October 16, 2017.
cc This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
This report presents the results of a feasibility study on a cyclotron-based neutron source for boron neutron-capture therapy (BNCT). Neutron yields from a beryllium target bombarded by a proton beam accelerated by a cyclotron were calculated using the GEANT4 simulation tool kit. The calculations were performed with different proton energies and different target thicknesses to find the changes in neutron spectra and yield at various angles. The main parameters for the design of a target with a neutron reflector were determined based on the calculated results, and epithermal neutron fluxes generated from the target were calculated. The epithermal neutron flux generated by a proton beam with an energy lower than 20 MeV was not sufficient for BNCT. However the flux generated by a 30 MeV, 500 $\mu$A proton beam was 1.03$\times$10$^{9}$ n/cm$^{2}$$\cdot$s, which satisfies the flux recommandation for a BNCT neutron source. 
PACS numbers: 29.25.Dz, 87.56.N-
Keywords: PET cyclotron, BNCT, Neutron source, Monte carlo, GEANT4

March 2018, 68 (3)
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