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A Evaluating Investigation on the Proton Boron Fusion Enhanced Proton Therapy (PBFEPT) by using Simulation Method
New Phys.: Sae Mulli
Published online October 29, 2018;  
© 2018 New Physics: Sae Mulli.

Dong LIU , SueLynn Lee, Jong-Kwan Woo*
Received September 11, 2018; Revised October 25, 2018; Accepted October 29, 2018.
Abstract
Radiation therapy is a kind of therapy method by delivering sufficiently high doses to target cells, concurrently delivering the dose to neighboring normal tissues as low as possible. As an advanced radiation therapy method, proton therapy has the more ideal dose distribution compare to electron and photon, benefit from the Bragg peak. Recently, an enhanced proton therapy that based on proton boron ($^{11}$B) fusion reaction is proposed. For this method, the alpha emitters from proton boron fusion reactions are utilized to improve the dose deposition in the target. A few studies have been carried out confirming this method by using the Monte Carlo N-Particle (MCNP) code. In our study, the mathematical method and GEometry ANd Tracking (GEANT4) toolkit are combined used to evaluate and analyzed the dose distribution of the Proton Boron ($^{11}$B) Fusion Enhanced Proton Therapy (PBFEPT) method. Through calculate the emitters of proton boron ($^{11}$B) fusion reactions based on related cross-section, and calculated the dose distribution of alpha emitters by using Geant4 toolkit, it can be found that the PBFEPT may relatively enhance the dose deposition in target volume. This shows an agreement with previous studies.


December 2018, 68 (12)
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