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Analysis of the Temperature and the Impedance Characteristics in the Gelatin Methacryloyl Hydrogel Crosslinking Process
New Phys.: Sae Mulli 2018; 68: 1147~1150
Published online October 31, 2018;
© 2018 New Physics: Sae Mulli.

Junhee PARK1, Taekyun YOO1, Jiseung LEE2, Chan Heum PARK2, Jae-Hyeon KO3, Moongyu JANG*4

1 Department of Nano-Medical Devices Engineering, Hallym University, Chuncheon 24252, Korea
2 Nano-Bio Regenerative Medical Institute, School of Medicine, Hallym University, Chuncheon 24252, Korea
3 Department of Physics, Hallym University, Chuncheon 24252, Korea
4 Department of Nano-Medical Devices Engineering and Department of Materials Science and Engineering, Hallym University, Chuncheon 24252, Korea
Correspondence to:
Received July 30, 2018; Revised August 20, 2018; Accepted August 20, 2018.
cc This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
In this study, the impedance and the temperature changes of gelatin methacryloyl, a protein based hydrogel used for various studies such as cell culture studies, were measured in real time. Sensors capable of simultaneously measuring the impedance and the temperature were fabricated using semiconductor and microelectromechanical systems (MEMS) processes. The occurrence of an endothermic reaction in the crosslinking of methacrylic anhydride, a crosslinking agent, was confirmed by the measurement of the temperature. Also, the measured impedance monotonically decreased during the gelatin methacryloyl hydrogel process.
PACS numbers: 07.07.Df, 82.39.Jn
Keywords: GelMA, Sensor, ECIS, Impedance, Temperature

January 2019, 69 (1)
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