The Integrated Science topics covered, week-by-week for the fall and spring semesters.
Fall | Spring | ||
---|---|---|---|
week | Topics | week | Topics |
1 | Intro and course overview. Biology as computation. Central Dogma. | 1 | Graphs & networks. Sequence alignment. |
2 | Intro to probability and Bayesian analysis. Equilibria, energy, and steady state. The Lac operon as a paradigm for gene regulation. | 2 | Sequence search algorithms. Finding sequence motifs. |
3 | Classical and molecular genetics. | 3 | Bayesian inference, probability & Markov models. |
4 | Math primer. Introduction to computation and differential equations. | 4 | Phylogenetic trees. Computational grammar. Gene finding. |
5 | Linear algebra. The cell division cycle. | 5 | Determining protein and nucleic acid structure. EXAM 1. |
6 | Linear algebra. The cell division cycle. EXAM1 | 6 | Protein structure. Enzyme mechanism. Dynamical systems. |
7 | Introduction to thermodynamics, entropy, temperature. | 7 | Enzyme mechanism. Dynamical systems. Cell structure. |
8 | Statistical mechanics. Chemistry of bonding. | 8 | Dynamical systems. Cell structure. Neuroscience |
9 | Statistical mechanics. Chemistry of cellular molecules. | 9 | Facial recognition. Population genetics. EXAM2. |
10 | Statistical mechanics. Cellular energy budget. Cooperativity. EXAM 2 | 10 | Population genetics. Stochastic phenomena in biology. Symmetry breaking. |
11 | Diffusion. Gene regulation. Evolution of development. | 11 | Simulating stochastic processes. Evolutionary thinking. |
12 | Diffusion. Gene regulation. Membranes. | 12 | Evolution of development. History & origin of life. |
13 | Reaction-diffusion systems. Electrostatics. Thanksgiving! | 13 | Watch this space! EXAM3. |
14 | Capacitors. Photosynthesis, oxidation, reduction. ATP synthesis. EXAM 3. |