npsm 새물리 New Physics : Sae Mulli

pISSN 0374-4914 eISSN 2289-0041


Research Paper

New Phys.: Sae Mulli 2019; 69: 215-220

Published online February 28, 2019

Copyright © New Physics: Sae Mulli.

Evaluation of Proton-Boron Fusion-Enhanced Proton Therapy (PBFEPT) by Using a Simulation Method

Dong LIU1, Sue Lynn LEE2, Jong-Kwan WO*3

1 BK21plus Clean Energy Convergence and Integration Center for Human Resources Training and Education, Jeju National University, Jeju 63243, Korea 

2 Division of Engineering, Cambridge University, Cambridgeshire, England

3 Department of Physics, Jeju National University, Jeju 63243, Korea


Received: September 11, 2018; Revised: October 25, 2018; Accepted: October 29, 2018

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Radiation therapy is a technique for delivering sufficiently high doses to target cells while keeping the dose to neighboring normal tissues as low as possible. As an advanced radiation therapy method, proton therapy has a more ideal dose distribution than either electron or photon therapy due to the Bragg peak. Recently, an enhanced proton therapy based on the proton-boron ($^{11}$B) fusion reaction was proposed. For this method, alpha emitters from proton-boron fusion reactions are utilized to improve the dose deposition in the target. A few studies have confirmed this method by using the Monte Carlo N-Particle (MCNP) code. In our study, a mathematical method and the GEometry ANd Tracking (GEANT4) toolkit are combined to evaluate and analyze the dose distribution of the proton-boron ($^{11}$B) fusion-enhanced proton therapy (PBFEPT) method. Calculations of both the emitters of proton-boron ($^{11}$B) fusion reactions based on related cross-sections and the dose distribution of alpha emitters by using Geant4 toolkit, PBFEPT is found relatively to enhance the dose deposition in the target volume. This results agrees with those of previous studies.

Keywords: Proton therapy, Proton-boron ($^{11}$B) fusion-enhanced proton therapy (PBFEPT), Monte Carlo method

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